Mourinho thinks there are six contenders to win the championship, but he has warned Manchester United and Tottenham Hotspur that they could find themselves cut adrift if they allow the gap to leaders Arsenal to grow.
And while the Portuguese insists there are no clear favourites, he feels that the strength of City's squad gives Manuel Pellegrini's side an advantage.
"I don't think we can speak about favourites but we can say that one team is top of the league and some are a little bit far, but I keep thinking that all six teams are title contenders," he said on Tuesday.
"But I keep saying that the team with more responsibilities to win it because their squad is quite unique is Manchester City."
Chelsea sit four points behind Arsenal in second place and two points above third-place City ahead of the mid-week round of fixtures, when Mourinho's side visit second-bottom Sunderland on Wednesday.
United and Tottenham, however, are well off the pace, trailing Arsenal by nine and 10 points respectively, and Mourinho feels that they are already in danger of slipping out of contention.
"United are nine points behind Arsenal. It's a gap. Nine points is a gap, Tottenham 10. That's a gap. It's not a gap for us," he said